The Position

The Computational Biophysics group within PTDU has an opening for a talented scientist to help shape the implementation and application of computational tools and algorithms to accelerate candidate selection and developability risk assessment. Our group uses computer modeling and simulations to study the dynamical behavior and properties of different protein modalities, with the ultimate aim of better understanding the developability risks, guiding candidate selection, and providing molecule re-engineering insights to improve stability. We work closely with different groups throughout Pharma Technical Development (PTD) and our Research organization. The successful candidate will participate in our vision toward further and smoother integration of in-silico develop-ability prediction tools within the organization, from helping with processing new modeling requests to developing new methods and tools to address the modeling needs for next generation biologic drugs.

Qualifications:

• Bachelor’s Degree or higher in physics, chemistry, materials science, bioinformatics, computational science or a related discipline, with 3-4 years of experience after their Bachelor’s Degree

• Proficiency in at least one modern computer programming language such as Python and bash scripting, and data visualization tools like matplotlib, seaborn

• Strong familiarity with topics of protein and macromolecular structures and their physical and chemical stability properties

• Knowledge of statistical techniques and concepts (regression, properties of distributions, statistical tests and proper usage, etc.) and experience with applications.

• A drive to learn and master new computational skills.

• Familiarity with high-performance scientific computing and the Linux environment is a plus.

• Experience with at least one of the commonly used molecular modeling and simulation packages such as MOE or Pymol is desired.

• Effective verbal and written communication skills with a demonstrated ability to work within multi-disciplinary teams

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $97,400 to $192,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

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Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

Genentech requires all new hires to be fully vaccinated against COVID-19 as of their start date. This requirement is a condition of employment at Genentech, and it applies regardless of whether the position is located at a Genentech campus or is fully remote. If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited as a result of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.